"Lil Louie" Cottrell is the great-grandson of "Old Man" Cottrell, and grandson of the "Prez" Cottrell. The younger Cottrell literally grew up on stage at the feet of his famed grandfather. He was often photographed on stage, sitting in between the legs of Louis, Jr. The younger Cottrell began his professional career with the Young Olympia Brass Band, then under the tutelage of Milton Batiste. "Lil Louie" then joined the Young Tuxedo Brass Band, a band both elder Cottrells paraded with. Louis Cottrell would later join Dr. Michael White's Original Liberty Jazz Band, in which he first recorded, "New Year's Eve Live At The Village Van Guard," with special guest, Wynton Marsalis.
Louis Cottrell played with numerous other jazz ensembles throughout New Orleans in addition to leading his own band, the Original Creole Jazz Band. Mr. Cottrell performed with many of the veterans of his grandfather's band including Danny Barker, his cousins, Placide and Gerald Adams, Teddy Riley, Wendell Eugene and Walter Lewis.